Go Back   Punjabi Junktion » :- Life Style -: » Health | Fitness

New tool to measure toxicity in smokers

This is a discussion on New tool to measure toxicity in smokers within the Health | Fitness forums, part of the :- Life Style -: category; New tool to measure toxicity in smokers New York: A three-dimensional model of human respiratory tissue can offer an improved ...

Reply
  #1  
Old 03-27-2015
Laado
 
Pill New tool to measure toxicity in smokers

New tool to measure toxicity in smokers

New York: A three-dimensional model of human respiratory tissue can offer an improved platform to measure the impact of chemicals, like those found in cigarette smoke, or other aerosols on the lung, a new study says.

The tissue model that the researchers assessed is called MucilAir. Traditional lab-based tests use cell lines that do not reflect normal lung structure and physiology, and in some cases have reduced, or loss of, key metabolic processes, the researchers noted.


Representational picture

Consequently, the long-term toxicological response of the cells can differ from what actually happens in humans, the study to be published in the journal Toxicology in Vitro noted.

"The combined weight of evidence from proteomics, gene expression and protein activity demonstrates that the MucilAir system is far better than continuous cell lines for assessing the effect of repeated exposure to inhaled chemicals and toxicants," says Emmanuel Minet, senior scientist at British American Tobacco.

The scientists assessed the effectiveness of MucilAir by growing human respiratory epithelial cells at the air-liquid interface on nasal cells.

The results showed that the cells in the test model remained viable for at least six months, which makes this tissue model suitable for testing the impact of repeated exposures over a prolonged period, as in the case of the typical smoker.

"Our results give clear supporting evidence that MucilAira, has the potential to be used to test not only the effect of acute doses of toxicants and medicines but also the effect of repeated doses over time," the researchers noted.
Sponsored Links
Reply

Thread Tools
Display Modes



PunjabiJunktion.Co.In tested by Norton Security PunjabiJunktion.Co.In tested by McAfee Security
All times are GMT +5.5. The time now is 07:01 AM. Ad Management plugin by PJ Tech Team